The 6th International Conference on High Pressure Bioscience and Biotechnology (HPBB2010) will be held in Freising (near Munich, Germany), from August 28th to September 1st, 2010. HPBB conferences bring together scientists, students and professionals to maximize synergy in high pressure bioscience and biotechnology, understanding and tuning protein thermodynamics and folding, lipid structure and function, signaling and transcription, in systems from food processing to cell biology to deep-subsurface environments.